Varaico: Literature-Extracted Genetic Variants

Gene:MAP2K7
Variant:p.C360Splc

MAP2K7

110 papers

RefSeq Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself...

Pfam Domains

Pkinaseaa 120–380UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase 7

HGNC Previous Symbol

PRKMK7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_145185.4
p.C360Splc
c.1080-1G>T
Surrounding Variants
1 paper
NM_145185.4
p.L361F
c.1081C>T
1 paper
NM_145185.4
p.R382C
c.1144C>T
1 paper
NM_145185.4
p.R382H
c.1145G>A
1 paper
NM_145185.4
p.E384V
c.1151A>T
1 paper
NM_145185.4
p.L386M
c.1156C>A
1 paper
NM_145185.4
p.A391V
c.1172C>T
1 paper
NM_145185.4
p.F394_K395del2
c.1180_1184del6
1 paper
NM_145185.4
p.D396N
c.1186G>A
1 paper
NM_145185.4
p.G408S
c.1222G>A
3 papers
NM_145185.4
p.V409I
c.1225G>A
1 paper
NM_145185.4
p.P413H
c.1238C>A
1 paper
NM_145185.4
p.S355A
c.1063T>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."