Varaico: Literature-Extracted Genetic Variants

Gene:MAP3K10
Variant:p.A17T

MAP3K10

110 papers

RefSeq Summary

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thu...

Pfam Domains

SH3_9aa 23–77UCSCVariant SH3 domain
PK_Tyr_Ser-Thraa 98–357UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 10

HGNC Previous Symbol

MLK2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002446.4
p.A17T
c.49G>A
Surrounding Variants
1 paper
NM_002446.4
p.T14A
c.40A>G
1 paper
NM_002446.4
p.G13D
c.38G>A
1 paper
NM_002446.4
p.T14_P16del3
c.40_47del9
1 paper
NM_002446.4
p.E11*
c.31G>T
1 paper
NM_002446.4
p.E5del1
c.13_14delGAG
1 paper
NM_002446.4
p.E33*
c.97G>T
1 paper
NM_002446.4
p.L46L
c.138T>A
1 paper
NM_002446.4
p.V68V
c.204G>A
1 paper
NM_002446.4
p.A85T
c.253G>A
1 paper
NM_002446.4
p.I93N
c.278T>A
1 paper
NM_002446.4
p.Q99L
c.296A>T
1 paper
NM_002446.4
p.V106Fs
c.317delinsTGFs
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."