Varaico: Literature-Extracted Genetic Variants

MAP3K11

124 papers

RefSeq Summary

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK k...

Pfam Domains

SH3_9aa 48–101UCSCVariant SH3 domain

PK_Tyr_Ser-Thraa 117–376UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 11

HGNC Previous Symbols

MLK3; PTK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002419.4

p.A75A

c.225A>G

Surrounding Variants

1 paper

NM_002419.4

p.R73R

c.219G>T

1 paper

NM_002419.4

p.K64N

c.192G>C

1 paper

NM_002419.4

p.Q91*

c.271C>T

1 paper

NM_002419.4

p.D58N

c.172G>A

1 paper

NM_002419.4

p.G89_G93del0

c.267_278del12

1 paper

NM_002419.4

p.E53D

c.159G>T

1 paper

NM_002419.4

p.E53D

c.159G>C

1 paper

NM_002419.4

p.Y99F

c.296A>T

1 paper

NM_002419.4

p.Y99C

c.296A>G

1 paper

NM_002419.4

p.T47T

c.141A>C

1 paper

NM_002419.4

p.G104G

c.312C>T

1 paper

NM_002419.4

p.G105C

c.313G>T