Varaico: Literature-Extracted Genetic Variants

Gene:MAP3K14
Variant:p.E334K

MAP3K14

652 papers

RefSeq Summary

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence simila...

Pfam Domains

Pkinaseaa 401–650UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 14

HGNC Alias Symbols

NIK; HSNIK; FTDCR1B

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003954.5
p.E334K
c.1000G>A
Surrounding Variants
1 paper
NM_003954.5
p.V338insFs
c.1012_1013insT
1 paper
NM_003954.5
p.H328Q
c.984T>G
1 paper
NM_003954.5
p.H328Q
c.984T>A
1 paper
NM_003954.5
p.A340S
c.1018G>T
1 paper
NM_003954.5
p.A340T
c.1018G>A
1 paper
NM_003954.5
p.H339_A340delFs
c.1017_1018delCA
1 paper
NM_003954.5
p.L341insFs
c.1022_1023insT
1 paper
NM_003954.5
p.G326insFs
c.977_978insC
1 paper
NM_003954.5
p.G326S
c.976G>A
1 paper
NM_003954.5
p.R325insFs
c.974dupG
3 papers
NM_003954.5
p.V345M
c.1033G>A
1 paper
NM_003954.5
p.S321N
c.962G>A
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