Varaico: Literature-Extracted Genetic Variants

Gene:MAP3K14
Variant:p.P299R

MAP3K14

652 papers

RefSeq Summary

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence simila...

Pfam Domains

Pkinaseaa 401–650UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 14

HGNC Alias Symbols

NIK; HSNIK; FTDCR1B

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003954.5
p.P299R
c.896C>G
Surrounding Variants
1 paper
NM_003954.5
p.L301L
c.903G>A
1 paper
NM_003954.5
p.L301delFs
c.903delC
1 paper
NM_003954.5
p.S302N
c.905G>A
1 paper
NM_003954.5
p.K303T
c.908A>C
3 papers
NM_003954.5
p.C306fs
c.916_917fs
2 papers
NM_003954.5
p.C306delFs
c.916delA
1 paper
NM_003954.5
p.S292C
c.874A>T
1 paper
NM_003954.5
p.D291N
c.871G>A
1 paper
NM_003954.5
p.C289_V290del2
c.865_869del6
1 paper
NM_003954.5
p.C289insFs
c.865_866insA
1 paper
NM_003954.5
p.K286insFs
c.858dupA
1 paper
NM_003954.5
p.L313L
c.937C>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."