Varaico: Literature-Extracted Genetic Variants

Gene:MAP3K14
Variant:p.F269Y

MAP3K14

652 papers

RefSeq Summary

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence simila...

Pfam Domains

Pkinaseaa 401–650UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 14

HGNC Alias Symbols

NIK; HSNIK; FTDCR1B

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003954.5
p.F269Y
c.806T>A
Surrounding Variants
1 paper
NM_003954.5
p.P268S
c.802C>T
1 paper
NM_003954.5
p.P259P
c.777C>A
1 paper
NM_003954.5
p.P259L
c.776C>T
1 paper
NM_003954.5
p.E281_S282insFs
c.843_844insG
1 paper
NM_003954.5
p.S282A
c.844T>G
1 paper
NM_003954.5
p.H256_P257insFs
c.768_769insAG
1 paper
NM_003954.5
p.T255T
c.765G>C
1 paper
NM_003954.5
p.L280_F283delFs
c.838_847del10
1 paper
NM_003954.5
p.P254fs
c.760_761fs
1 paper
NM_003954.5
p.K286insFs
c.858dupA
1 paper
NM_003954.5
p.C289insFs
c.865_866insA
2 papers
NM_003954.5
p.G249S
c.745G>A
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