Varaico: Literature-Extracted Genetic Variants

Gene:MAP3K14
Variant:p.G248E

MAP3K14

652 papers

RefSeq Summary

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence simila...

Pfam Domains

Pkinaseaa 401–650UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 14

HGNC Alias Symbols

NIK; HSNIK; FTDCR1B

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003954.5
p.G248E
c.743G>A
Surrounding Variants
1 paper
NM_003954.5
p.G248R
c.742G>C
1 paper
NM_003954.5
p.G248R
c.742G>A
2 papers
NM_003954.5
p.G249S
c.745G>A
1 paper
NM_003954.5
p.H243D
c.727C>G
1 paper
NM_003954.5
p.P254fs
c.760_761fs
1 paper
NM_003954.5
p.T255T
c.765G>C
1 paper
NM_003954.5
p.W240R
c.718T>A
1 paper
NM_003954.5
p.H256_P257insFs
c.768_769insAG
1 paper
NM_003954.5
p.P259L
c.776C>T
1 paper
NM_003954.5
p.N237S
c.710A>G
1 paper
NM_003954.5
p.P259P
c.777C>A
1 paper
NM_003954.5
p.S231T
c.692G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."