Varaico: Literature-Extracted Genetic Variants

Gene:MAP3K14
Variant:p.R167W

MAP3K14

652 papers

RefSeq Summary

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence simila...

Pfam Domains

Pkinaseaa 401–650UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 14

HGNC Alias Symbols

NIK; HSNIK; FTDCR1B

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003954.5
p.R167W
c.499A>T
Surrounding Variants
2 papers
NM_003954.5
p.R167G
c.499A>G
1 paper
NM_003954.5
p.L165P
c.494T>C
1 paper
NM_003954.5
p.P169insFs
c.506dupC
1 paper
NM_003954.5
p.Q171*
c.511C>T
1 paper
NM_003954.5
p.E172D
c.516G>T
1 paper
NM_003954.5
p.V159E
c.476T>A
1 paper
NM_003954.5
p.G158E
c.473G>A
1 paper
NM_003954.5
p.T175T
c.525C>G
1 paper
NM_003954.5
p.A157G
c.470C>G
8 papers
NM_003954.5
p.A157T
c.469G>A
1 paper
NM_003954.5
p.V178M
c.532G>A
1 paper
NM_003954.5
p.A155A
c.465T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."