Varaico: Literature-Extracted Genetic Variants

Gene:MAP3K14
Variant:p.K147N

MAP3K14

652 papers

RefSeq Summary

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence simila...

Pfam Domains

Pkinaseaa 401–650UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 14

HGNC Alias Symbols

NIK; HSNIK; FTDCR1B

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003954.5
p.K147N
c.441G>C
Surrounding Variants
1 paper
NM_003954.5
p.K147N
c.441G>T
2 papers
NM_003954.5
p.K148N
c.444G>T
2 papers
NM_003954.5
p.K148N
c.444G>C
1 paper
NM_003954.5
p.R146W
c.436C>T
2 papers
NM_003954.5
p.K145I
c.434A>T
1 paper
NM_003954.5
p.K149del1
c.445_446delCTT
1 paper
NM_003954.5
p.K145*
c.433A>T
1 paper
NM_003954.5
p.K145E
c.433A>G
1 paper
NM_003954.5
p.S151A
c.451T>G
1 paper
NM_003954.5
p.K144_K145ins5
c.430_434ins15
1 paper
NM_003954.5
p.R143Q
c.428G>A
1 paper
NM_003954.5
p.K152insFs
c.454_455insC
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."