Varaico: Literature-Extracted Genetic Variants

Gene:MAP3K14
Variant:p.L42I

MAP3K14

652 papers

RefSeq Summary

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence simila...

Pfam Domains

Pkinaseaa 401–650UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 14

HGNC Alias Symbols

NIK; HSNIK; FTDCR1B

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_003954.5
p.L42I
c.124C>A
Surrounding Variants
1 paper
NM_003954.5
p.K41N
c.123G>T
1 paper
NM_003954.5
p.K41N
c.123G>C
1 paper
NM_003954.5
p.K41R
c.122A>G
1 paper
NM_003954.5
p.K41E
c.121A>G
1 paper
NM_003954.5
p.V45L
c.133G>T
1 paper
NM_003954.5
p.V39I
c.115G>A
1 paper
NM_003954.5
p.S38A
c.112T>G
1 paper
NM_003954.5
p.E46K
c.136G>A
1 paper
NM_003954.5
p.V45_E46Fs
c.134_136delinsCCFs
1 paper
NM_003954.5
p.V45_E46delFs
c.135_136delCC
1 paper
NM_003954.5
p.K47*
c.139A>T
1 paper
NM_003954.5
p.S37R
c.109A>C
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."