Varaico: Literature-Extracted Genetic Variants

Gene:MAP3K14
Variant:p.M1L

MAP3K14

652 papers

RefSeq Summary

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence simila...

Pfam Domains

Pkinaseaa 401–650UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 14

HGNC Alias Symbols

NIK; HSNIK; FTDCR1B

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_003954.5
p.M1L
c.1A>C
Surrounding Variants
2 papers
NM_003954.5
p.M1L
c.1A>T
1 paper
NM_003954.5
p.M1I
c.3G>T
1 paper
NM_003954.5
p.M1I
c.3G>C
2 papers
NM_003954.5
p.M1I
c.3G>A
1 paper
NM_003954.5
p.M1delFs
c.2delA
1 paper
NM_003954.5
p.A2insFs
c.4_5insT
1 paper
NM_003954.5
p.V3M
c.7G>A
1 paper
NM_003954.5
p.V3E
c.8T>A
1 paper
NM_003954.5
p.M4L
c.10A>T
5 papers
NM_003954.5
p.M4I
c.12G>C
4 papers
NM_003954.5
p.M4I
c.12G>A
1 paper
NM_003954.5
p.A7A
c.21C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."