Varaico: Literature-Extracted Genetic Variants

MAP3K20

136 papers

RefSeq Summary

This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha mot...

Pfam Domains

PK_Tyr_Ser-Thraa 16–260UCSCProtein tyrosine and serine/threonine kinase

SAM_2aa 337–408UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 20

HGNC Alias Symbols

MLTKalpha; MLTKbeta; ZAK; MLTK; MLK7; MRK

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_016653.3

p.W172*

c.515G>A

Surrounding Variants

3 papers

NM_016653.3

p.W172*

c.516G>A

1 paper

NM_016653.3

p.T169A

c.505A>G

1 paper

NM_016653.3

p.G168G

c.504A>T

2 papers

NM_016653.3

p.S165A

c.493T>G

3 papers

NM_016653.3

p.M164fs

c.490_491fs

2 papers

NM_016653.3

p.M164fs

c.490_491fs

3 papers

NM_016653.3

p.M164delFs

c.490_491delAT

1 paper

NM_016653.3

p.T162A

c.484A>G

2 papers

NM_016653.3

p.T161A

c.481A>G

1 paper

NM_016653.3

p.H160fs

c.478_479fs

1 paper

NM_016653.3

p.E185K

c.553G>A

1 paper

NM_016653.3

p.F157L

c.471C>A