Varaico: Literature-Extracted Genetic Variants

MAP3K20

136 papers

RefSeq Summary

This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha mot...

Pfam Domains

PK_Tyr_Ser-Thraa 16–260UCSCProtein tyrosine and serine/threonine kinase

SAM_2aa 337–408UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 20

HGNC Alias Symbols

MLTKalpha; MLTKbeta; ZAK; MLTK; MLK7; MRK

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_016653.3

p.C273R

c.817T>C

Surrounding Variants

1 paper

NM_016653.3

p.C273F

c.818G>T

1 paper

NM_016653.3

p.C273_N274del2

c.817_821del6

1 paper

NM_016653.3

p.P270L

c.809C>T

1 paper

NM_016653.3

p.L277V

c.829C>G

1 paper

NM_016653.3

p.L269F

c.805C>T

3 papers

NM_016653.3

p.N279_K280del1

c.837_839delCAA

1 paper

NM_016653.3

p.T267T

c.801G>A

3 papers

NM_016653.3

p.T267M

c.800C>T

2 papers

NM_016653.3

p.K280_A281insT

c.838_842ins3

1 paper

NM_016653.3

p.A281T

c.841G>A

2 papers

NM_016653.3

p.A281A

c.843G>A

1 paper

NM_016653.3

p.L260V

c.778C>G