Varaico: Literature-Extracted Genetic Variants

MAP3K20

136 papers

RefSeq Summary

This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha mot...

Pfam Domains

PK_Tyr_Ser-Thraa 16–260UCSCProtein tyrosine and serine/threonine kinase

SAM_2aa 337–408UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 20

HGNC Alias Symbols

MLTKalpha; MLTKbeta; ZAK; MLTK; MLK7; MRK

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016653.3

p.I421I

c.1263T>C

Surrounding Variants

1 paper

NM_016653.3

p.E432D

c.1296G>C

1 paper

NM_016653.3

p.E432D

c.1296G>T

1 paper

NM_016653.3

p.L438del1

c.1312_1313delCTG

1 paper

NM_016653.3

p.G449E

c.1346G>A

1 paper

NM_016653.3

p.H396R

c.1187A>G

1 paper

NM_016653.3

p.L379V

c.1135C>G

1 paper

NM_016653.3

p.G375E

c.1124G>A

1 paper

NM_016653.3

p.E370*

c.1108G>T

5 papers

NM_016653.3

p.F368C

c.1103T>G

1 paper

NM_016653.3

p.G355V

c.1064G>T

2 papers

NM_016653.3

p.W347S

c.1040G>C

1 paper

NM_016653.3

p.C346*

c.1038T>A