Varaico: Literature-Extracted Genetic Variants

MAP3K20

136 papers

RefSeq Summary

This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha mot...

Pfam Domains

PK_Tyr_Ser-Thraa 16–260UCSCProtein tyrosine and serine/threonine kinase

SAM_2aa 337–408UCSCSAM domain (Sterile alpha motif)

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 20

HGNC Alias Symbols

MLTKalpha; MLTKbeta; ZAK; MLTK; MLK7; MRK

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_016653.3

p.D570H

c.1708G>C

Surrounding Variants

2 papers

NM_016653.3

p.R580W

c.1738C>T

1 paper

NM_016653.3

p.G607V

c.1820G>T

1 paper

NM_016653.3

p.R617fs

c.1849_1850fs

1 paper

NM_016653.3

p.R634G

c.1900A>G

1 paper

NM_016653.3

p.S687P

c.2059T>C

1 paper

NM_016653.3

p.G694E

c.2081G>A

1 paper

NM_016653.3

p.Y696H

c.2086T>C

1 paper

NM_016653.3

p.R716S

c.2148G>T

1 paper

NM_016653.3

p.L722R

c.2165T>G

1 paper

NM_016653.3

p.R735S

c.2205G>C

1 paper

NM_016653.3

p.R735S

c.2205G>T

1 paper

NM_016653.3

p.P747delFs

c.2241delT