Varaico: Literature-Extracted Genetic Variants

Gene:MAP3K4

MAP3K4

247 papers

RefSeq Summary

The central core of each mitogen-activated protein kinase (MAPK) pathway is a conserved cascade of 3 protein kinases: an activated MAPK kinase kinase (MAPKKK) phosphorylates and activates a specific M...

Pfam Domains

MEKK4_Naa 51–1269UCSCMEKK4 N-terminal
MEKK4_Naa 1169–1215UCSCMEKK4 N-terminal
Pkinaseaa 1343–1601UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 4

HGNC Previous Symbol

MEKK4

Papers
RefSeq ID
Protein change
DNA change
1–12 of 334 variants
23 papers
NM_005922.4
p.P1189_A1190del1
c.3566_3568delCTG
10 papers
NM_005922.4
p.G1366R
c.4096G>A
10 papers
NM_005922.4
p.G1366R
c.4096G>C
8 papers
NM_005922.4
p.R157H
c.470G>A
6 papers
NM_005922.4
p.W396delFs
c.1186_1187delTG
4 papers
NM_005922.4
p.N195H
c.583A>C
4 papers
NM_005922.4
p.L397delFs
c.1189_1190delTT
4 papers
NM_005922.4
p.Q584H
c.1752G>C
4 papers
NM_005922.4
p.Q584H
c.1752G>T
4 papers
NM_005922.4
p.S1185_H1186del2
c.3553_3557del6
4 papers
NM_005922.4
p.S1185_H1186del1
c.3554_3556delGCC
4 papers
NM_005922.4
p.P1189_A1190del2
c.3565_3569del6
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."