Varaico: Literature-Extracted Genetic Variants

MAP3K7

372 papers

RefSeq Summary

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and con...

Pfam Domains

PK_Tyr_Ser-Thraa 36–284UCSCProtein tyrosine and serine/threonine kinase

Map3k7claa 513–605UCSCMAP3K7 C-terminal-like protein

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 7

HGNC Previous Symbol

TAK1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 201 variants

7 papers

NM_145331.3

p.G246Splc

c.737-7A>G

6 papers

NM_145331.3

p.V50del1

c.148_149delAAC

6 papers

NM_145331.3

p.V100E

c.299T>A

6 papers

NM_145331.3

p.G110C

c.328G>T

5 papers

NM_145331.3

p.G168R

c.502G>C

5 papers

NM_145331.3

p.G168R

c.502G>A

5 papers

NM_003188.4

p.P485L

c.1454C>T

5 papers

NM_145331.3

p.P512L

c.1535C>T

4 papers

NM_145331.3

p.V42del1

c.124_125delAAC

4 papers

NM_145331.3

p.G45V

c.134G>T

4 papers

NM_145331.3

p.R44_G45del0

c.130_135del6

4 papers

NM_145331.3

p.G48E

c.143G>A