Varaico: Literature-Extracted Genetic Variants

MAP3K7

372 papers

RefSeq Summary

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and con...

Pfam Domains

PK_Tyr_Ser-Thraa 36–284UCSCProtein tyrosine and serine/threonine kinase

Map3k7claa 513–605UCSCMAP3K7 C-terminal-like protein

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 7

HGNC Previous Symbol

TAK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

10 papers

NM_003188.4

p.P485L

c.1454C>T

NM_145331.3

p.P512L

c.1535C>T

Surrounding Variants

1 paper

NM_003188.4

p.P485R

c.1454C>G

1 paper

NM_003188.4

p.P485S

c.1453C>T

1 paper

NM_003188.4

p.P485A

c.1453C>G

1 paper

NM_145331.3

p.L510P

c.1529T>C

1 paper

NM_145331.3

p.E539Q

c.1615G>C

1 paper

NM_145331.3

p.Q508K

c.1522C>A

1 paper

NM_145331.3

p.D488V

c.1463A>T

1 paper

NM_145331.3

p.D488N

c.1462G>A

1 paper

NM_145331.3

p.D555E

c.1665C>G

1 paper

NM_145331.3

p.D555E

c.1665C>A

1 paper

NM_145331.3

p.Q562E

c.1684C>G

1 paper

NM_145331.3

p.S565A

c.1693T>G