Varaico: Literature-Extracted Genetic Variants

MAP3K7

372 papers

RefSeq Summary

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and con...

Pfam Domains

PK_Tyr_Ser-Thraa 36–284UCSCProtein tyrosine and serine/threonine kinase

Map3k7claa 513–605UCSCMAP3K7 C-terminal-like protein

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 7

HGNC Previous Symbol

TAK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_145331.3

p.W241G

c.721T>G

Surrounding Variants

4 papers

NM_145331.3

p.W241R

c.721T>C

4 papers

NM_145331.3

p.W241R

c.721T>A

1 paper

NM_145331.3

p.I239insFs

c.716_717insT

3 papers

NM_145331.3

p.R238Q

c.713G>A

1 paper

NM_145331.3

p.F237S

c.710T>C

3 papers

NM_145331.3

p.G246ins2

c.736_737ins6

1 paper

NM_145331.3

p.K227N

c.681A>T

1 paper

NM_145331.3

p.K227N

c.681A>C

1 paper

NM_145331.3

p.R226Q

c.677G>A

1 paper

NM_145331.3

p.R226W

c.676C>T

1 paper

NM_145331.3

p.R225R

c.675T>C

1 paper

NM_145331.3

p.W220*

c.660G>A