Varaico: Literature-Extracted Genetic Variants

MAP3K7

372 papers

RefSeq Summary

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and con...

Pfam Domains

PK_Tyr_Ser-Thraa 36–284UCSCProtein tyrosine and serine/threonine kinase

Map3k7claa 513–605UCSCMAP3K7 C-terminal-like protein

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 7

HGNC Previous Symbol

TAK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_145331.3

p.T187S

c.559A>T

Surrounding Variants

3 papers

NM_145331.3

p.T187A

c.559A>G

3 papers

NM_145331.3

p.T187I

c.560C>T

1 paper

NM_145331.3

p.T187S

c.560C>G

1 paper

NM_145331.3

p.N188T

c.563A>C

2 papers

NM_145331.3

p.T184A

c.550A>G

2 papers

NM_145331.3

p.G191R

c.571G>C

2 papers

NM_145331.3

p.G191R

c.571G>A

1 paper

NM_145331.3

p.G191A

c.572G>C

1 paper

NM_145331.3

p.S192N

c.575G>A

1 paper

NM_145331.3

p.A179D

c.536C>A

1 paper

NM_145331.3

p.W195_M196insT

c.583_587ins3

1 paper

NM_145331.3

p.M196V

c.586A>G