Varaico: Literature-Extracted Genetic Variants

MAP3K7

372 papers

RefSeq Summary

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and con...

Pfam Domains

PK_Tyr_Ser-Thraa 36–284UCSCProtein tyrosine and serine/threonine kinase

Map3k7claa 513–605UCSCMAP3K7 C-terminal-like protein

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 7

HGNC Previous Symbol

TAK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_145331.3

p.K172R

c.515A>G

Surrounding Variants

1 paper

NM_145331.3

p.L171L

c.511C>T

1 paper

NM_145331.3

p.C174Y

c.521G>A

1 paper

NM_145331.3

p.C174W

c.522T>G

1 paper

NM_145331.3

p.V170I

c.508G>A

1 paper

NM_145331.3

p.D175A

c.524A>C

1 paper

NM_145331.3

p.T169A

c.505A>G

1 paper

NM_145331.3

p.T169fs

c.505_506fs

5 papers

NM_145331.3

p.G168R

c.502G>C

5 papers

NM_145331.3

p.G168R

c.502G>A

2 papers

NM_145331.3

p.F176insFs

c.528dupT

1 paper

NM_145331.3

p.T178A

c.532A>G

1 paper

NM_145331.3

p.A179D

c.536C>A