Varaico: Literature-Extracted Genetic Variants

MAP3K7

372 papers

RefSeq Summary

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and con...

Pfam Domains

PK_Tyr_Ser-Thraa 36–284UCSCProtein tyrosine and serine/threonine kinase

Map3k7claa 513–605UCSCMAP3K7 C-terminal-like protein

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 7

HGNC Previous Symbol

TAK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_145331.3

p.M131V

c.391A>G

Surrounding Variants

1 paper

NM_145331.3

p.H129Y

c.385C>T

4 papers

NM_145331.3

p.Y125_A127del3

c.373_380del9

1 paper

NM_145331.3

p.T126N

c.377C>A

3 papers

NM_145331.3

p.A130_L135del6

c.388_404del18

1 paper

NM_145331.3

p.C137S

c.409T>A

1 paper

NM_145331.3

p.V141M

c.421G>A

1 paper

NM_145331.3

p.A142V

c.425C>T

1 paper

NM_145331.3

p.H117Y

c.349C>T

1 paper

NM_145331.3

p.V115E

c.344T>A

1 paper

NM_145331.3

p.K150R

c.449A>G

1 paper

NM_145331.3

p.K150N

c.450A>T

1 paper

NM_145331.3

p.K150N

c.450A>C