Varaico: Literature-Extracted Genetic Variants

MAP3K7

372 papers

RefSeq Summary

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and con...

Pfam Domains

PK_Tyr_Ser-Thraa 36–284UCSCProtein tyrosine and serine/threonine kinase

Map3k7claa 513–605UCSCMAP3K7 C-terminal-like protein

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase 7

HGNC Previous Symbol

TAK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_145331.3

p.Y106*

c.318T>A

Surrounding Variants

1 paper

NM_145331.3

p.Y106*

c.318T>G

1 paper

NM_145331.3

p.E108K

c.322G>A

6 papers

NM_145331.3

p.G110C

c.328G>T

1 paper

NM_145331.3

p.G110V

c.329G>T

1 paper

NM_145331.3

p.G110D

c.329G>A

1 paper

NM_145331.3

p.Y113D

c.337T>G

6 papers

NM_145331.3

p.V100E

c.299T>A

1 paper

NM_145331.3

p.N114K

c.342T>A

1 paper

NM_145331.3

p.V115E

c.344T>A

1 paper

NM_145331.3

p.H117Y

c.349C>T

1 paper

NM_145331.3

p.T126N

c.377C>A

4 papers

NM_145331.3

p.Y125_A127del3

c.373_380del9