Varaico: Literature-Extracted Genetic Variants

MAP4K3

104 papers

RefSeq Summary

This gene encodes a member of the mitogen-activated protein kinase kinase kinase kinase family. The encoded protein activates key effectors in cell signalling, among them c-Jun. Alternatively spliced ...

Pfam Domains

Pkinaseaa 1–210UCSCProtein kinase domain

Pkinaseaa 16–273UCSCProtein kinase domain

CNHaa 571–863UCSCCNH domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase kinase 3

HGNC Previous Symbol

RAB8IPL1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003618.4

p.Q473H

c.1419A>C

Surrounding Variants

2 papers

NM_003618.4

p.Q473H

c.1419A>T

1 paper

NM_003618.4

p.P476A

c.1426C>G

1 paper

NM_003618.4

p.G466A

c.1397G>C

1 paper

NM_003618.4

p.P481A

c.1441C>G

1 paper

NM_003618.4

p.S465P

c.1393T>C

1 paper

NM_003618.4

p.M464I

c.1392G>T

1 paper

NM_003618.4

p.M464I

c.1392G>C

1 paper

NM_003618.4

p.M464I

c.1392G>A

1 paper

NM_003618.4

p.P484A

c.1450C>G

1 paper

NM_001270425.2

p.C441S

c.1322G>C

1 paper

NM_003618.4

p.P485A

c.1453C>G

1 paper

NM_003618.4

p.P485fs

c.1453_1454fs