Varaico: Literature-Extracted Genetic Variants

Gene:MAP4K5
Variant:p.K571R

MAP4K5

72 papers

RefSeq Summary

This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal casc...

Pfam Domains

Pkinaseaa 20–277UCSCProtein kinase domain
CNHaa 521–815UCSCCNH domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase kinase 5

HGNC Alias Symbols

KHS1; KHS

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_006575.6
p.K571R
c.1712A>G
Surrounding Variants
1 paper
NM_006575.6
p.G570V
c.1709G>T
1 paper
NM_006575.6
p.C626S
c.1876T>A
1 paper
NM_006575.6
p.C626S
c.1877G>C
1 paper
NM_006575.6
p.E569Splc
c.1705+1G>A
1 paper
NM_006575.6
p.V628D
c.1883T>A
4 papers
NM_006575.6
p.T633M
c.1898C>T
1 paper
NM_006575.6
p.K662_H663Splc
c.1987-4G>T
1 paper
NM_006575.6
p.E682Q
c.2044G>C
1 paper
NM_006575.6
p.E684_Y685insA
c.2050_2054ins3
1 paper
NM_006575.6
p.N699_Q700insC
c.2095_2099ins3
1 paper
NM_006575.6
p.G720_A721insA
c.2158_2162ins3
1 paper
NM_006575.6
p.G495V
c.1484G>T
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