Varaico: Literature-Extracted Genetic Variants

Gene:MAP4K5
Variant:p.V492A

MAP4K5

72 papers

RefSeq Summary

This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal casc...

Pfam Domains

Pkinaseaa 20–277UCSCProtein kinase domain
CNHaa 521–815UCSCCNH domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase kinase 5

HGNC Alias Symbols

KHS1; KHS

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_006575.6
p.V492A
c.1475T>C
Surrounding Variants
1 paper
NM_006575.6
p.P481Q
c.1442C>A
1 paper
NM_006575.6
p.K475K
c.1425A>G
1 paper
NM_006575.6
p.G495R
c.1483G>C
1 paper
NM_006575.6
p.G495R
c.1483G>A
1 paper
NM_006575.6
p.G495V
c.1484G>T
1 paper
NM_006575.6
p.A412_K416delFs
c.1234_1247del14
1 paper
NM_006575.6
p.A412delFs
c.1234delC
1 paper
NM_006575.6
p.A412fs
c.1234_1235fs
2 papers
NM_006575.6
p.P407L
c.1220C>T
1 paper
NM_006575.6
p.Y401H
c.1201T>C
1 paper
NM_006575.6
p.S384L
c.1151C>T
1 paper
NM_006575.6
p.E569Splc
c.1705+1G>A
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