Varaico: Literature-Extracted Genetic Variants

Gene:MAP4K5
Variant:p.R265fs

MAP4K5

72 papers

RefSeq Summary

This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal casc...

Pfam Domains

Pkinaseaa 20–277UCSCProtein kinase domain
CNHaa 521–815UCSCCNH domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase kinase 5

HGNC Alias Symbols

KHS1; KHS

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
3 papers
NM_006575.6
p.R265fs
c.793_794fs
Surrounding Variants
1 paper
NM_006575.6
p.R265delFs
c.793delT
1 paper
NM_006575.6
p.R265fs
c.793_794fs
1 paper
NM_006575.6
p.R270K
c.809G>A
1 paper
NM_006575.6
p.S248P
c.742T>C
1 paper
NM_006575.6
p.H274Y
c.820C>T
1 paper
NM_006575.6
p.V294V
c.882G>A
1 paper
NM_006575.6
p.L240_K241insFs
c.720_721insA
1 paper
NM_006575.6
p.S233_N234insFs
c.699_700insC
1 paper
NM_006575.6
p.F228_L229insFs
c.684_685insA
1 paper
NM_006575.6
p.I206L
c.616A>C
1 paper
NM_006575.6
p.V204A
c.611T>C
1 paper
NM_006575.6
p.A188A
c.564A>G
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."