Varaico: Literature-Extracted Genetic Variants

Gene:MAP4K5
Variant:p.E54Q

MAP4K5

72 papers

RefSeq Summary

This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal casc...

Pfam Domains

Pkinaseaa 20–277UCSCProtein kinase domain
CNHaa 521–815UCSCCNH domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase kinase kinase kinase 5

HGNC Alias Symbols

KHS1; KHS

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_006575.6
p.E54Q
c.160G>C
Surrounding Variants
1 paper
NM_006575.6
p.G43_A46delins
c.128_137delinsC
1 paper
NM_006575.6
p.E44K
c.130G>A
1 paper
NM_006575.6
p.R38T
c.113G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."