Varaico: Literature-Extracted Genetic Variants

Gene:MAPK1
Variant:p.E322K

MAPK1

2,460 papers

RefSeq Summary

This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are inv...

Pfam Domains

Pkinaseaa 25–313UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase 1

HGNC Previous Symbols

PRKM2; PRKM1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
79 papers
NM_002745.5
p.E322K
c.964G>A
Surrounding Variants
1 paper
NM_002745.5
p.E322*
c.964G>T
1 paper
NM_002745.5
p.D321D
c.963C>T
2 papers
NM_002745.5
p.D321E
c.963C>G
2 papers
NM_002745.5
p.D321E
c.963C>A
5 papers
NM_002745.5
p.E322V
c.965A>T
3 papers
NM_002745.5
p.E322A
c.965A>C
1 paper
NM_002745.5
p.E322insFs
c.965_966insC
5 papers
NM_002745.5
p.D321V
c.962A>T
5 papers
NM_002745.5
p.D321G
c.962A>G
2 papers
NM_002745.5
p.D321A
c.962A>C
31 papers
NM_002745.5
p.D321N
c.961G>A
1 paper
NM_002745.5
p.S320_D321insFs
c.960_961insG
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."