Varaico: Literature-Extracted Genetic Variants

Gene:MAPK3
Variant:p.R189L

MAPK3

1,486 papers

RefSeq Summary

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellu...

Pfam Domains

Pkinaseaa 42–330UCSCProtein kinase domain

Gene Aliases

HGNC Name

mitogen-activated protein kinase 3

HGNC Previous Symbol

PRKM3

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_002746.3
p.R189L
c.566G>T
Surrounding Variants
3 papers
NM_002746.3
p.R189Q
c.566G>A
2 papers
NM_002746.3
p.R189W
c.565C>T
4 papers
NM_002746.3
p.I190T
c.569T>C
1 paper
NM_002746.3
p.A188V
c.563C>T
1 paper
NM_002746.3
p.L187P
c.560T>C
1 paper
NM_002746.3
p.A191V
c.572C>T
1 paper
NM_002746.3
p.A191D
c.572C>A
1 paper
NM_002746.3
p.D192N
c.574G>A
3 papers
NM_002746.3
p.G186D
c.557G>A
2 papers
NM_002746.3
p.D192G
c.575A>G
1 paper
NM_002746.3
p.D192E
c.576T>A
1 paper
NM_002746.3
p.G186R
c.556G>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."