Varaico: Literature-Extracted Genetic Variants

MARK2

1,200 papers

RefSeq Summary

This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stabi...

Pfam Domains

Pkinaseaa 53–304UCSCProtein kinase domain

UBAaa 324–360UCSCUBA/TS-N domain

KA1aa 744–788UCSCKinase associated domain 1

Gene Aliases

HGNC Name

microtubule affinity regulating kinase 2

HGNC Previous Symbol

EMK1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001039469.3

p.K61M

c.182A>T

Surrounding Variants

3 papers

NM_001039469.3

p.K61R

c.182A>G

1 paper

NM_001039469.3

p.G60G

c.180C>G

1 paper

NM_001039469.3

p.G60A

c.179G>C

1 paper

NM_001039469.3

p.G62insFs

c.185_186insA

1 paper

NM_001039469.3

p.G62V

c.185G>T

1 paper

NM_001039469.3

p.T58T

c.174C>T

1 paper

NM_001039469.3

p.I59_F64delFs

c.175_190del16

1 paper

NM_001039469.3

p.K66M

c.197A>T

1 paper

NM_001039469.3

p.L56H

c.167T>A

1 paper

NM_001039469.3

p.V67M

c.199G>A

1 paper

NM_001039469.3

p.L55H

c.164T>A

2 papers

NM_001039469.3

p.L55F

c.163C>T