Varaico: Literature-Extracted Genetic Variants

Gene:MC4R
Variant:p.S20G

MC4R

858 papers

RefSeq Summary

The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by...

Pfam Domains

7tm_1aa 61–302UCSC7 transmembrane receptor (rhodopsin family)

Gene Aliases

HGNC Name

melanocortin 4 receptor

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_005912.3
p.S20G
c.58A>G
Surrounding Variants
1 paper
NM_005912.3
p.S19R
c.57C>G
1 paper
NM_005912.3
p.S19R
c.57C>A
6 papers
NM_005912.3
p.S19delFs
c.55delT
5 papers
NM_005912.3
p.S19fs
c.55_56fs
1 paper
NM_005912.3
p.S19G
c.55A>G
1 paper
NM_005912.3
p.S19R
c.55A>C
2 papers
NM_005912.3
p.R18insFs
c.54dupC
1 paper
NM_005912.3
p.Y21C
c.62A>G
10 papers
NM_005912.3
p.R18L
c.53G>T
15 papers
NM_005912.3
p.R18H
c.53G>A
1 paper
NM_005912.3
p.Y21Y
c.63C>T
6 papers
NM_005912.3
p.Y21*
c.63C>G
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