Varaico: Literature-Extracted Genetic Variants

Gene:MCL1
Variant:p.V265L

MCL1

397 papers

RefSeq Summary

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell sur...

Pfam Domains

Bcl-2aa 60–159UCSCApoptosis regulator proteins, Bcl-2 family

Gene Aliases

HGNC Name

MCL1 apoptosis regulator, BCL2 family member

HGNC Alias Symbols

BCL2L3; Mcl-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_021960.5
p.V265L
c.793G>C
Surrounding Variants
1 paper
NM_021960.5
p.V265L
c.793G>T
1 paper
NM_021960.5
p.V265M
c.793G>A
1 paper
NM_021960.5
p.V265A
c.794T>C
1 paper
NM_021960.5
p.I264F
c.790A>T
1 paper
NM_021960.5
p.R263delins
c.788_789delinsAA
1 paper
NM_021960.5
p.T266N
c.797C>A
2 papers
NM_021960.5
p.R263K
c.788G>A
1 paper
NM_021960.5
p.L267F
c.799C>T
1 paper
NM_021960.5
p.L267V
c.799C>G
2 papers
NM_021960.5
p.G262V
c.785G>T
1 paper
NM_021960.5
p.G262C
c.784G>T
2 papers
NM_021960.5
p.N260K
c.780C>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."