Varaico: Literature-Extracted Genetic Variants

Gene:MCL1
Variant:p.P81S

MCL1

397 papers

RefSeq Summary

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell sur...

Pfam Domains

Bcl-2aa 60–159UCSCApoptosis regulator proteins, Bcl-2 family

Gene Aliases

HGNC Name

MCL1 apoptosis regulator, BCL2 family member

HGNC Alias Symbols

BCL2L3; Mcl-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_021960.5
p.P81S
c.241C>T
Surrounding Variants
1 paper
NM_021960.5
p.P80Q
c.239C>A
1 paper
NM_021960.5
p.P80fs
c.238_239fs
1 paper
NM_021960.5
p.P80S
c.238C>T
1 paper
NM_021960.5
p.P79_P80delins
c.237_238delinsCT
1 paper
NM_021960.5
p.G83C
c.247G>T
2 papers
NM_021960.5
p.P79T
c.235C>A
1 paper
NM_021960.5
p.G83D
c.248G>A
1 paper
NM_021960.5
p.R78L
c.233G>T
1 paper
NM_021960.5
p.R78Q
c.233G>A
1 paper
NM_021960.5
p.A84S
c.250G>T
1 paper
NM_021960.5
p.A84T
c.250G>A
1 paper
NM_021960.5
p.A84D
c.251C>A
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