Varaico: Literature-Extracted Genetic Variants

Gene:MCL1
Variant:p.P31insFs

MCL1

397 papers

RefSeq Summary

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell sur...

Pfam Domains

Bcl-2aa 60–159UCSCApoptosis regulator proteins, Bcl-2 family

Gene Aliases

HGNC Name

MCL1 apoptosis regulator, BCL2 family member

HGNC Alias Symbols

BCL2L3; Mcl-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_021960.5
p.P31insFs
c.92_93insT
Surrounding Variants
1 paper
NM_021960.5
p.P31Q
c.92C>A
1 paper
NM_021960.5
p.G32*
c.94G>T
1 paper
NM_021960.5
p.G32R
c.94G>A
1 paper
NM_021960.5
p.R30R
c.90C>A
1 paper
NM_021960.5
p.G32V
c.95G>T
2 papers
NM_021960.5
p.R30C
c.88C>T
1 paper
NM_021960.5
p.G33R
c.97G>C
1 paper
NM_021960.5
p.G33R
c.97G>A
2 papers
NM_021960.5
p.G33E
c.98G>A
1 paper
NM_021960.5
p.T29N
c.86C>A
1 paper
NM_021960.5
p.R34*
c.100C>T
1 paper
NM_021960.5
p.R34G
c.100C>G
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