Varaico: Literature-Extracted Genetic Variants

Gene:MCL1
Variant:p.S25R

MCL1

397 papers

RefSeq Summary

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell sur...

Pfam Domains

Bcl-2aa 60–159UCSCApoptosis regulator proteins, Bcl-2 family

Gene Aliases

HGNC Name

MCL1 apoptosis regulator, BCL2 family member

HGNC Alias Symbols

BCL2L3; Mcl-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_021960.5
p.S25R
c.75C>A
Surrounding Variants
1 paper
NM_021960.5
p.S25S
c.75C>T
1 paper
NM_021960.5
p.G26C
c.76G>T
1 paper
NM_021960.5
p.G26V
c.77G>T
1 paper
NM_021960.5
p.S25G
c.73A>G
3 papers
NM_021960.5
p.L21_G24del0
c.61_72del12
2 papers
NM_021960.5
p.G26G
c.78C>T
1 paper
NM_021960.5
p.G27C
c.79G>T
1 paper
NM_021960.5
p.G27D
c.80G>A
1 paper
NM_021960.5
p.G18_G22delFs
c.53_66del14
1 paper
NM_021960.5
p.A23T
c.67G>A
1 paper
NM_021960.5
p.A28V
c.83C>T
1 paper
NM_021960.5
p.G22G
c.66G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."