Varaico: Literature-Extracted Genetic Variants

Gene:MCL1
Variant:p.G20G

MCL1

397 papers

RefSeq Summary

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell sur...

Pfam Domains

Bcl-2aa 60–159UCSCApoptosis regulator proteins, Bcl-2 family

Gene Aliases

HGNC Name

MCL1 apoptosis regulator, BCL2 family member

HGNC Alias Symbols

BCL2L3; Mcl-1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_021960.5
p.G20G
c.60C>G
Surrounding Variants
1 paper
NM_021960.5
p.G20V
c.59G>T
1 paper
NM_021960.5
p.G20D
c.59G>A
2 papers
NM_021960.5
p.G20R
c.58G>C
1 paper
NM_021960.5
p.L21fs
c.61_62fs
1 paper
NM_021960.5
p.L21delFs
c.61delA
1 paper
NM_021960.5
p.A19A
c.57C>T
3 papers
NM_021960.5
p.A19fs
c.55_56fs
1 paper
NM_021960.5
p.A19insFs
c.56_57insG
2 papers
NM_021960.5
p.A19delFs
c.55delC
2 papers
NM_021960.5
p.G22V
c.65G>T
1 paper
NM_021960.5
p.A19T
c.55G>A
1 paper
NM_021960.5
p.G22G
c.66G>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."