Varaico: Literature-Extracted Genetic Variants

MCM10

72 papers

RefSeq Summary

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein c...

Pfam Domains

OB_MCM10aa 249–379UCSCMCM10 OB-fold

zf-primaseaa 382–427UCSCPrimase zinc finger

zf-CCCH_Mcm10aa 524–817UCSCMcm10, CCCH-type zinc motif

Mcm10aa 818–873UCSCMcm10, C-terminal zinc binding motif

Gene Aliases

HGNC Name

minichromosome maintenance 10 replication initiation factor

HGNC Alias Symbols

PRO2249; CNA43; DNA43

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_018518.5

p.E117Splc

c.349+56C>T

Surrounding Variants

1 paper

NM_018518.5

p.L101F

c.301C>T

1 paper

NM_018518.5

p.T96S

c.287C>G

1 paper

NM_018518.5

p.T96S

c.286A>T

1 paper

NM_018518.5

p.G79fs

c.235_236fs

2 papers

NM_018518.5

p.G79delFs

c.236delG

1 paper

NM_018518.5

p.F78S

c.233T>C

1 paper

NM_018518.5

p.T76I

c.227C>T

1 paper

NM_018518.5

p.D60G

c.179A>G

1 paper

NM_018518.5

p.T56A

c.166A>G

1 paper

NM_018518.5

p.D51E

c.153C>A

1 paper

NM_018518.5

p.D51E

c.153C>G

1 paper

NM_018518.5

p.F46V

c.136T>G