Varaico: Literature-Extracted Genetic Variants

MCM10

72 papers

RefSeq Summary

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein c...

Pfam Domains

OB_MCM10aa 249–379UCSCMCM10 OB-fold

zf-primaseaa 382–427UCSCPrimase zinc finger

zf-CCCH_Mcm10aa 524–817UCSCMcm10, CCCH-type zinc motif

Mcm10aa 818–873UCSCMcm10, C-terminal zinc binding motif

Gene Aliases

HGNC Name

minichromosome maintenance 10 replication initiation factor

HGNC Alias Symbols

PRO2249; CNA43; DNA43

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_018518.5

p.E152Splc

c.455-1G>C

Surrounding Variants

1 paper

NM_018518.5

p.S170A

c.508T>G

1 paper

NM_018518.5

p.E176A

c.527A>C

2 papers

NM_018518.5

p.A194P

c.580G>C

1 paper

NM_018518.5

p.S150F

c.449C>T

1 paper

NM_018518.5

p.Q140K

c.418C>A

1 paper

NM_018518.5

p.K134R

c.401A>G

1 paper

NM_018518.5

p.K127R

c.380A>G

1 paper

NM_018518.5

p.E117Splc

c.349+56C>T

1 paper

NM_018518.5

p.L101F

c.301C>T

1 paper

NM_018518.5

p.T96S

c.287C>G

1 paper

NM_018518.5

p.T96S

c.286A>T

1 paper

NM_018518.5

p.G79fs

c.235_236fs