Varaico: Literature-Extracted Genetic Variants

MCM10

72 papers

RefSeq Summary

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein c...

Pfam Domains

OB_MCM10aa 249–379UCSCMCM10 OB-fold

zf-primaseaa 382–427UCSCPrimase zinc finger

zf-CCCH_Mcm10aa 524–817UCSCMcm10, CCCH-type zinc motif

Mcm10aa 818–873UCSCMcm10, C-terminal zinc binding motif

Gene Aliases

HGNC Name

minichromosome maintenance 10 replication initiation factor

HGNC Alias Symbols

PRO2249; CNA43; DNA43

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_018518.5

p.T447P

c.1339A>C

Surrounding Variants

1 paper

NM_018518.5

p.S448R

c.1342A>C

1 paper

NM_018518.5

p.E451V

c.1352A>T

1 paper

NM_018518.5

p.P439Q

c.1316C>A

1 paper

NM_018518.5

p.Q430*

c.1288C>T

1 paper

NM_018518.5

p.L429L

c.1285C>T

1 paper

NM_018518.5

p.R426H

c.1277G>A

4 papers

NM_018518.5

p.R426C

c.1276C>T

1 paper

NM_018518.5

p.S423R

c.1269C>A

1 paper

NM_018518.5

p.S423R

c.1269C>G

1 paper

NM_018518.5

p.S423R

c.1267A>C

3 papers

NM_018518.5

p.A417V

c.1250C>T

1 paper

NM_018518.5

p.C399Y

c.1196G>A