Varaico: Literature-Extracted Genetic Variants

MCM3

127 papers

RefSeq Summary

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein c...

Pfam Domains

MCM_Naa 16–104UCSCMCM N-terminal domain

MCM_OBaa 110–245UCSCMCM OB domain

MCMaa 280–505UCSCMCM P-loop domain

MCM_lidaa 520–607UCSCMCM AAA-lid domain

MCM_lidaa 566–653UCSCMCM AAA-lid domain

WHD_MCM3_Caa 691–762UCSCMCM3-like, winged helix domain

Gene Aliases

HGNC Name

minichromosome maintenance complex component 3

HGNC Previous Names

minichromosome maintenance deficient (S. cerevisiae) 3; MCM3 minichromosome maintenance deficient 3 (S. cerevisiae)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002388.6

p.N68K

c.204T>G

Surrounding Variants

1 paper

NM_002388.6

p.N68K

c.204T>A

1 paper

NM_002388.6

p.E72*

c.214G>T

1 paper

NM_002388.6

p.R64Splc

c.192-1G>A

1 paper

NM_002388.6

p.V84_A85insC

c.250_254ins3

1 paper

NM_002388.6

p.S86Y

c.257C>A

1 paper

NM_002388.6

p.I87V

c.259A>G

1 paper

NM_002388.6

p.S105G

c.313A>G

1 paper

NM_002388.6

p.F106insFs

c.316_317insC

1 paper

NM_002388.6

p.S112A

c.334T>G

1 paper

NM_002388.6

p.L121R

c.362T>G

1 paper

NM_002388.6

p.C123Y

c.368G>A

1 paper

NM_002388.6

p.V124G

c.371T>G