Varaico: Literature-Extracted Genetic Variants

MCM7

118 papers

RefSeq Summary

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein...

Pfam Domains

MCM_Naa 10–140UCSCMCM N-terminal domain

MCM_OBaa 148–281UCSCMCM OB domain

MCMaa 320–541UCSCMCM P-loop domain

MCM_lidaa 557–641UCSCMCM AAA-lid domain

WHD_MCM7aa 663–719UCSCDNA replication licensing factor MCM7, winged helix

Gene Aliases

HGNC Name

minichromosome maintenance complex component 7

HGNC Alias Symbols

CDC47; PPP1R104

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005916.5

p.A398T

c.1192G>A

Surrounding Variants

1 paper

NM_005916.5

p.A398V

c.1193C>T

1 paper

NM_005916.5

p.R400H

c.1199G>A

1 paper

NM_005916.5

p.G360R

c.1078G>A

1 paper

NM_005916.5

p.L358R

c.1073T>G

1 paper

NM_005916.5

p.I344T

c.1031T>C

1 paper

NM_005916.5

p.A337V

c.1010C>T

1 paper

NM_005916.5

p.K335K

c.1005G>A

1 paper

NM_005916.5

p.Y333C

c.998A>G

1 paper

NM_005916.5

p.R286R

c.858A>G

1 paper

NM_005916.5

p.R282C

c.844C>T

1 paper

NM_005916.5

p.V273I

c.817G>A

1 paper

NM_005916.5

p.P267L

c.800C>T