malic enzyme 1

malic enzyme 1, NADP(+)-dependent, cytosolic

malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))

NADP-dependent malic enzyme

Malic enzyme 1

NADP-ME

This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq, Jul 2008].

Varaico: Literature-Extracted Genetic Variants

ME1

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Name