Varaico: Literature-Extracted Genetic Variants

Gene:ME3
Variant:p.P45S

ME3

51 papers

RefSeq Summary

Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-...

Pfam Domains

malicaa 114–295UCSCMalic enzyme, N-terminal domain
Malic_Maa 305–557UCSCMalic enzyme, NAD binding domain

Gene Aliases

HGNC Name

malic enzyme 3

HGNC Previous Name

malic enzyme 3, NADP(+)-dependent, mitochondrial

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_001161586.3
p.P45S
c.133C>T
Surrounding Variants
1 paper
NM_001161586.3
p.L46Q
c.137T>A
1 paper
NM_001161586.3
p.K48R
c.143A>G
1 paper
NM_001161586.3
p.D52N
c.154G>A
1 paper
NM_001161586.3
p.D52G
c.155A>G
1 paper
NM_001161586.3
p.A29V
c.86C>T
1 paper
NM_001161586.3
p.C19G
c.55T>G
1 paper
NM_001161586.3
p.G6R
c.16G>C
1 paper
NM_001161586.3
p.G6R
c.16G>A
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