Varaico: Literature-Extracted Genetic Variants

MED12

1,019 papers

RefSeq Summary

The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Me...

Pfam Domains

Med12aa 104–161UCSCTranscription mediator complex subunit Med12

Med12-LCEWAVaa 286–757UCSCEukaryotic Mediator 12 subunit domain

Med12-PQLaa 1819–2022UCSCEukaryotic Mediator 12 catenin-binding domain

Gene Aliases

HGNC Name

mediator complex subunit 12

HGNC Previous Symbols

TNRC11; FGS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005120.3

p.E35*

c.103G>T

Surrounding Variants

1 paper

NM_005120.3

p.E35K

c.103G>A

1 paper

NM_005120.3

p.E35Q

c.103G>C

1 paper

NM_005120.3

p.E35insFs

c.103_104insGC

1 paper

NM_005120.3

p.E35_L36del1

c.104_106delAAC

4 papers

NM_005120.3

p.E35_N40del0

c.105_119del15

2 papers

NM_005120.3

p.L36_Q43del0

c.107_127del21

2 papers

NM_005120.3

p.L36_Q43del0

c.106_129del24

1 paper

NM_005120.3

p.L36_T37delFs

c.106_109del4

1 paper

NM_005120.3

p.E35_G44del0

c.105_131del27

1 paper

NM_005120.3

p.E35insFs

c.103_104insG

1 paper

NM_005120.3

p.E35_A38del0

c.104_112del9

2 papers

NM_005120.3

p.D34G

c.101A>G