Varaico: Literature-Extracted Genetic Variants

MED12

1,019 papers

RefSeq Summary

The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Me...

Pfam Domains

Med12aa 104–161UCSCTranscription mediator complex subunit Med12

Med12-LCEWAVaa 286–757UCSCEukaryotic Mediator 12 subunit domain

Med12-PQLaa 1819–2022UCSCEukaryotic Mediator 12 catenin-binding domain

Gene Aliases

HGNC Name

mediator complex subunit 12

HGNC Previous Symbols

TNRC11; FGS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005120.3

p.L36_A38del0

c.107_112del6

Surrounding Variants

1 paper

NM_005120.3

p.L36M

c.106C>A

2 papers

NM_005120.3

p.N40ins3

c.118_119ins9

1 paper

NM_005120.3

p.L36fs

c.106_107fs

3 papers

NM_005120.3

p.T37_N40del0

c.110_118del9

2 papers

NM_005120.3

p.L36_V41del0

c.108_122del15

1 paper

NM_005120.3

p.L36_V41delFs

c.107_122del16

1 paper

NM_005120.3

p.E35D

c.105A>T

2 papers

NM_005120.3

p.L36del1

c.106_108delCTG

1 paper

NM_005120.3

p.L36_Q48del0

c.107_142del36

1 paper

NM_005120.3

p.L36Q

c.107T>A

15 papers

NM_005120.3

p.L36P

c.107T>C

52 papers

NM_005120.3

p.L36R

c.107T>G