Varaico: Literature-Extracted Genetic Variants

MED12

1,019 papers

RefSeq Summary

The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Me...

Pfam Domains

Med12aa 104–161UCSCTranscription mediator complex subunit Med12

Med12-LCEWAVaa 286–757UCSCEukaryotic Mediator 12 subunit domain

Med12-PQLaa 1819–2022UCSCEukaryotic Mediator 12 catenin-binding domain

Gene Aliases

HGNC Name

mediator complex subunit 12

HGNC Previous Symbols

TNRC11; FGS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005120.3

p.A38_F45del0

c.112_135del24

Surrounding Variants

2 papers

NM_005120.3

p.A38_V41del0

c.113_121del9

2 papers

NM_005120.3

p.A38_N46del0

c.112_138del27

1 paper

NM_005120.3

p.A38_N47del0

c.112_141del30

5 papers

NM_005120.3

p.A38_A50del0

c.114_149del36

2 papers

NM_005120.3

p.A38_V51del0

c.113_151del39

1 paper

NM_005120.3

p.A38insFs

c.112_113ins8

2 papers

NM_005120.3

p.T37R

c.110C>G

1 paper

NM_005120.3

p.T37M

c.110C>T

1 paper

NM_005120.3

p.T37_V41del0

c.111_122del12

1 paper

NM_005120.3

p.A38insFs

c.112_113insAC

1 paper

NM_005120.3

p.A38_L39ins7

c.112_116ins21

1 paper

NM_005120.3

p.A38S

c.112G>T