Varaico: Literature-Extracted Genetic Variants

MED12

1,019 papers

RefSeq Summary

The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Me...

Pfam Domains

Med12aa 104–161UCSCTranscription mediator complex subunit Med12

Med12-LCEWAVaa 286–757UCSCEukaryotic Mediator 12 subunit domain

Med12-PQLaa 1819–2022UCSCEukaryotic Mediator 12 catenin-binding domain

Gene Aliases

HGNC Name

mediator complex subunit 12

HGNC Previous Symbols

TNRC11; FGS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

48 papers

NM_005120.3

p.Q43P

c.128A>C

Surrounding Variants

1 paper

NM_005120.3

p.Q43ins1

c.128_129insGTT

3 papers

NM_005120.3

p.Q43_G44del1

c.129_131delAGG

1 paper

NM_005120.3

p.Q43_F45del0

c.129_134del6

1 paper

NM_005120.3

p.Q43_N46delins

c.128_137delinsC

1 paper

NM_005120.3

p.Q43_P49del0

c.129_146del18

1 paper

NM_005120.3

p.Q43_A50del0

c.129_149del21

1 paper

NM_005120.3

p.Q43_G44insFs

c.129_130insT

1 paper

NM_005120.3

p.Q43H

c.129A>C

2 papers

NM_005120.3

p.Q43Q

c.129A>G

1 paper

NM_005120.3

p.Q43H

c.129A>T

1 paper

NM_005120.3

p.G44_N47del0

c.130_141del12

1 paper

NM_005120.3

p.G44_P49del0

c.130_147del18