Varaico: Literature-Extracted Genetic Variants

MED12

1,019 papers

RefSeq Summary

The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Me...

Pfam Domains

Med12aa 104–161UCSCTranscription mediator complex subunit Med12

Med12-LCEWAVaa 286–757UCSCEukaryotic Mediator 12 subunit domain

Med12-PQLaa 1819–2022UCSCEukaryotic Mediator 12 catenin-binding domain

Gene Aliases

HGNC Name

mediator complex subunit 12

HGNC Previous Symbols

TNRC11; FGS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005120.3

p.H984L

c.2951A>T

Surrounding Variants

1 paper

NM_005120.3

p.C982Y

c.2945G>A

1 paper

NM_005120.3

p.K988E

c.2962A>G

1 paper

NM_005120.3

p.G990W

c.2968G>T

1 paper

NM_005120.3

p.S994I

c.2981G>T

1 paper

NM_005120.3

p.S962delFs

c.2884delT

61 papers

NM_005120.3

p.R961W

c.2881C>T

20 papers

NM_005120.3

p.G958E

c.2873G>A

1 paper

NM_005120.3

p.G958V

c.2873G>T

2 papers

NM_005120.3

p.K956M

c.2867A>T

1 paper

NM_005120.3

p.G958ins8

c.2873_2874ins24

1 paper

NM_005120.3

p.V955G

c.2864T>G

2 papers

NM_005120.3

p.V954G

c.2861T>G