Varaico: Literature-Extracted Genetic Variants

MED12

1,019 papers

RefSeq Summary

The initiation of transcription is controlled in part by a large protein assembly known as the preinitiation complex. A component of this preinitiation complex is a 1.2 MDa protein aggregate called Me...

Pfam Domains

Med12aa 104–161UCSCTranscription mediator complex subunit Med12

Med12-LCEWAVaa 286–757UCSCEukaryotic Mediator 12 subunit domain

Med12-PQLaa 1819–2022UCSCEukaryotic Mediator 12 catenin-binding domain

Gene Aliases

HGNC Name

mediator complex subunit 12

HGNC Previous Symbols

TNRC11; FGS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005120.3

p.E1012D

c.3036A>C

Surrounding Variants

1 paper

NM_005120.3

p.E1012D

c.3036A>T

1 paper

NM_005120.3

p.N1014S

c.3041A>G

1 paper

NM_005120.3

p.S1011P

c.3031T>C

1 paper

NM_005120.3

p.E1009G

c.3026A>G

1 paper

NM_005120.3

p.R1016C

c.3046C>T

1 paper

NM_005120.3

p.V1008L

c.3022G>C

1 paper

NM_005120.3

p.V1008L

c.3022G>T

47 papers

NM_005120.3

p.N1007S

c.3020A>G

1 paper

NM_005120.3

p.A1018V

c.3053C>T

1 paper

NM_005120.3

p.F1021L

c.3061T>C

1 paper

NM_005120.3

p.F1021Y

c.3062T>A

1 paper

NM_005120.3

p.F1021L

c.3063C>A